top of page
Original peer-reviewed research articles

Chama M, Amadi B, Chandwe K, Besa E, Zyambo K, Shaikh N, Ndao M, Tarr P, Storer C, Head R, Kelly P. Transcriptomic analysis of enteropathy in Zambian children with severe acute malnutrition. EBiomedicine2019; in press.


Syed S, Al-BoniM, KhanMN, SadiqK, IqbalNT, MoskalukCA, KellyP, AmadiB, AliSAA, Moore SR, Brown DE. Assessment of machine learning detection of Environmental Enteropathy and celiac disease in children. JAMA Network Open 2019; 2: e195822. doi: 0.1001/jamanetworkopen.2019.5822.


PrayGod G, Rehman AM, Wells JCK, Chisenga M, Siame J, Jeremiah K, Kasonka L, Woodd S, Changalucha J, Kelly P, Koethe JR, Heimburger DC, Friis H, Filteau S. Effects on body composition and handgrip strength of a nutritional intervention for malnourished HIV-infected adults referred for antiretroviral therapy: a randomised controlled trial. J Nutr Sci2019; 8: e19. doi: 10.1017/jns.2019.15. eCollection 2019.


Kayamba V, Shibemba A, Zyambo K, Heimburger DC, Morgan D, Kelly P. HIV related hypochlorhydria does not appear to respond to anti-retroviral therapy in Zambian adults: a case control study. Pan Afr Med J 2018; 31: 128. doi: 10.11604/pamj.2018.31.128.11850. 


Kayamba V,  Kelly P. Delayed referral for diagnostic endoscopy is a contributing factor to late gastric cancer diagnosis in Zambia. Health Press Zambia Bull2019; 3: 14-19.


Bwakura-Dangarembizi M, Amadi B, Bourke CD, Robertson RC, Mwapenya B, Chandwe K, Kapoma C, Chifunda K, Majo F, Ngosa D, Chakara P, Chulu N, Masimba F, Mapurisa I, Besa E, Mutasa K, Mwakamui S, Runodamoto T, Humphrey JH, Ntozini R, Wells J, Manges AR, Swann J, Walker AS, Nathoo KJ, Kelly P, Prendergast AJ. Health Outcomes, Pathogenesis and Epidemiology of Severe Acute Malnutrition (HOPE-SAM): rationale and methods of a longitudinal observational study. BMJ Open2019;9: e023077. doi: 10.1136/bmjopen-2018-023077.


Ndulo N, Peters R, Macgregor K, Imasiku M, Amadi B, Kelly P. Infrequent small bowel intestinal bacterial overgrowth in malnourished Zambian children. Pan Afr Med J; in press.


Kayamba V, Zyambo K, Kelly P. Presence of blood in gastric juice: A sensitive marker for gastric cancer screening in a poor resource setting. PLoS One2018; 13: e0205185.doi: 10.1371/journal.pone.0205185.


Vinikoor MJ, Sinkala E, Kanunga A, Muchimba M, Nsokolo B, Chilengi R, Wandeler G, Mulenga J, Chisenga T, Bhattacharya D, Saag MS, Foster GR, Fried MW, Kelly P. Chronic hepatitis B virus monoinfection at a University hospital in Zambia. World J Hepatol2018; 10: 622-628. doi: 10.4254/wjh.v10.i9.622.


Mwanza-LisuloM, ChombaMS,ChamaM, BesaEC, FunjikaE, ZyamboK, BandaR, ImikenduM, SianongoS,HancockREW, LeeA, ChilengiR, StaggAJ, Namangala B, Kelly P. Retinoic acid elicits a coordinated expression of gut homing markers on T lymphocytes of Zambian men receiving oral Vivotif, but not Rotarix, Dukoral or OPVERO vaccines. Vaccine2018; 36: 4134-4141.


Kayamba V, Nicholls K, Morgan C, Kelly P. A seven-year retrospective review of colonoscopy records from a single centre in Zambia. Malawi Med J 2018; 30:17-21. 


Chongwe G, Michelo C, Sinkala E, Kayamba V, Nzaisenga J-B, Drobniewski F, Kelly P.  Mycobacterium aviumlysate induces matrix metalloproteinase-1 in intestinal tissue and peripheral blood: observations from selected hospital based Zambian adults. Int J Infect Dis 2018; 71:73-81.doi: 10.1016/j.ijid.2018.03.020.


Sinkala E, Zyambo K, Besa E, Kaonga P, Nsokolo B, Kayamba V, Vinikoor M, Zulu R, Bwalya M, Foster GR, Kelly P. Rifaximin reduces markers of inflammation and bacterial 16S rRNA in Zambian adults with hepatosplenic schistosomiasis: a randomized control trial. Am J Trop Med Hyg2018; 98:1152-1158. doi: 10.4269/ajtmh.17-0637.


Farràs M, Chandwe K, Mayneris-Perxachs J, Amadi B, Louis-Auguste J, Besa E, Zyambo K, Guerrant R, Kelly P, Swann JR. Characterizing the metabolic phenotype of intestinal villus blunting in Zambian children with severe acute malnutrition and persistent diarrhea. PLoS One 2018;13: e0192092.


Syed S, Dinallo V, Iqbal N, Di Iorio L, Di Fusco D, Guleria S, Amadi BC, Sadiq K, Moskaluk C, Ali A, Kelly P, Monteleone G. High SMAD7 and p-SMAD2,3 expression is associated with environmental enteropathy in children. PLoS Negl Trop Dis2018; 12: e0006224. doi: 10.1371/journal.pntd.0006224. 


Mutengo MM, Mduluza T, Kelly P, Mwansa JCL, Kwenda G, Musonda P, Chipeta J. Low IL-6, IL-10, TNF-α and high IL-13 cytokine levels are associated with severe hepatic fibrosis in Schistosoma mansonichronically exposed individuals. J Parasitol Res 2018; 9754060. doi:10.1155/2018/9754060.


Andrews B, Semmler MW, Muchemwa L, Kelly P, Lakhi S, Heimburger DC, Mabula C, Bwalya M, Bernard GR. Effect of an early resuscitation protocol on in-hospital mortality among adults with sepsis and hypotension: a randomized clinical trial. JAMA 2017; 318: 1233-1240. doi:10.1001/jama.2017.10913.


Nsokolo B, Kanunga A , Sinkala E , Zyambo Z, Kumwenda D, Chamab D, Muyinda G, Vinikoor M, Ijaz S, Tedder R, Elmdaah AKA, Jones M, Chiluba C, Mudenda V, Goldin RD, Foster G, Kelly P. Stage of disease in hepatitis B virus infection in Zambian adults is associated with large cell change but not well defined using classic biomarkers. Trans R Soc Trop Med Hyg 2017; 111: 425–432. 



Kayamba V, Shibemba A, Zyambo K, Heimburger D, Morgan D, Kelly P. High prevalence of gastric intestinal metaplasia detected by confocal laser endomicroscopy in Zambian adults. PLoS One2017; 12: e0184272. doi: 10.1371/journal.pone.0184272.


Amadi B, BesaE, ZyamboK, KaongaP, Louis-AugusteJ, ChandweK, TarrPI, DennoDM, NataroJP, FaubionW, SailerA, YeruvaS, BrantnerT, MurrayJA, PrendergastAJ, TurnerJR, Kelly P. Impaired barrier function and autoantibody generation in malnutrition enteropathy in Zambia. EBiomedicine2017; 22: 191-199. doi: 10.1016/j.ebiom.2017.07.017.


Filteau S, PrayGod G, Woodd SL, Friis H, Heimburger DC, Koethe JR, Kelly P, Kasonka L, Rehman AM. Nutritional status is the major factor affecting grip strength of African HIV patients before and during antiretroviral treatment. Trop Med Int Health2017; 22: 1302-1313. doi: 10.1111/tmi.12929.


Rehman AM, Woodd SL, Heimburger DC, Koethe JR, Friis H, PrayGod G, Kasonka L, Kelly P, Filteau S. Changes in serum phosphate and potassium and their effects on mortality in malnourished African HIV-infected adults starting antiretroviral therapy and given vitamins and minerals in lipid-based nutritional supplements: secondary analysis from the NUSTART trial. Br J Nutr2017; 117: 814-821. doi: 10.1017/S0007114517000721.


Kaonga P, Kaimoyo E, Besa E, Zyambo K, Sinkala E, Kelly P. Direct biomarkers of microbial translocation correlate with immune activation in adult Zambians with environmental enteropathy and hepatosplenic schistosomiasis. Am J Trop Med Hyg 2017; in press.


Rehman AM, Woodd SL, Heimburger DC, Koethe JR, Friis H, PrayGod G, Kasonka L, Kelly P, Filteau S. Changes in serum phosphate and potassium and their effects on mortality in malnourished African HIV-infected adults starting antiretroviral therapy and given vitamins and minerals in lipid-based nutritional supplements: secondary analysis from the NUSTART trial. Br J Nutr 2017; in press.


Chongwe G, Michelo C, Kelly P. Diagnostic yield of nontuberculous mycobacteria in patients booked for endoscopy at the University Teaching Hospital, Lusaka. BMC Res Notes 2017; 10: 27.


Simuyandi M, Kapulu MC, Kelly P. Antimicrobial peptide gene expression during oral vaccination: analysis of a randomised controlled trial. Clin Exp Immunol 2016; 186: 205-213. doi: 10.1111/cei.12848.


Woodd SL, Kelly P, Koethe JR, PrayGod G, Rehman AM, Chisenga M, Siame J, Heimburger DC, Friis H, Filteau S. Risk factors for mortality among malnourished HIV-infected adults eligible for antiretroviral therapy. BMC Infect Dis 2016; 16: 562.


Munkombwe D, Mungo TL, Michelo C, Kelly P, Chirwa S, Filteau S. Lipid-based nutrient supplements containing vitamins and minerals attenuate renal electrolyte loss in HIV/AIDS patients starting antiretroviral therapy: a randomized controlled trial in Zambia. Clin Nutr 2016; 13: e8-e14. doi: 10.1016/j.clnesp.2016.03.002.


Kelly P, Besa E, Zyambo K, Louis-Auguste J, Lees J, Banda T, Soko R, Banda R, Amadi B, Watson A. Endomicroscopic and transcriptomic analysis of impaired barrier function and malabsorption in environmental enteropathy. PLoS Negl Trop Dis 2016; 10: e0004600. doi:10.1371/journal.pntd.0004600.


Faubion WA, Camilleri MC, Murray JA, Kelly P, Kosek M, Enders F, Larson J, Boe, G, Dyer R, Singh R. A lactulose, rhamnose assay of intestinal permeability in the assessment of environmental enteric dysfunction. BMJ Global Health 2016; 1: e000066. doi:10.1136/bmjgh-2016-000066.


Chisenga CC, Kelly P. T cell subset profile in healthy Zambian adults at the University Teaching Hospital. Pan African Medical Journal 2016; 23:103. doi: 10.11604/pamj.2016.23.103.8547.


Praygod G, Blevins M, Woodd S, Rehman A, Jeremiah K, Friis H, Kelly P, Changalucha J, Heimburger D, Filteau S, Koethe J. A longitudinal study of systemic inflammation and recovery of lean body mass among malnourished HIV-infected adults starting antiretroviral therapy in Tanzania and Zambia. Eur J Clin Nutr 2016; 70: 499-504. doi: 10.1038/ejcn.2015.221.


Amadi B, Imasiku M, Sakala M, Banda R, Kelly P. Integration of HIV care into community management of acute childhood malnutrition permits good outcomes: retrospective analysis of three years of a programme in Lusaka. PLoS One 2016; 11: e0149218. doi:10.1371/journal.pone.0149218.


Asombang AW, Kayamba V, Lisulo MM, Trinkaus K, Mudenda V, Sinkala E, Mwanamakondo S, Banda T, Soko R, Kelly P. Esophageal squamous cell cancer in a highly endemic region. World J Gastroenterol 2016; 22: 2811-2817. doi: 10.3748/wjg.v22.i9.2811.


Sinkala E, Kapulu M, Besa E, Zyambo K, Chisoso NJ, Foster GR, Kelly P. Hepatosplenic schistosomiasis is characterised by high blood markers of  translocation, inflammation and fibrosis. Liver Int 2016; 36: 145-50. doi:10.1111/liv.12891.


Kayamba V, Monze M, Asombang AW, Zyambo K, Kelly P. Serological response to Epstein-Barr virus early antigen is associated with gastric cancer and Human immunodeficiency virus infection in Zambian adults: a case-control study. Pan African Med J 2016; 23: 45. doi:10.11604/pamj.2016.23.45.8503.


Rosa G, Kelly P, Clasen T. Consistency of use and effectiveness of household water treatment practices among urban and rural populations claiming to treat their drinking water at home: a case study in Zambia. Am J Trop Med Hyg 2016; 94: 445-55. doi: 10.4269/ajtmh.15-0563.


Kayamba V, Sinkala E, Mwanamakondo S, Soko R, Kawimbe B, Amadi B, Zulu I,  Nzai'senga J-B, Banda T, Mumba C, Phiri E, Munkonge P, Kelly P. Trends in upper gastrointestinal diagnosis over four decades in Lusaka, Zambia: a retrospective analysis of endoscopic findings. BMC Gastroenterology 2015; 15: 127. doi: 10.1186/s12876-015-0353-8.


James P, Friis H, Woodd S, Rehman AM, PrayGod G, Kelly P, Koethe JR, Filteau S. Minimal impact of an iron-fortified lipid-based nutrient supplement on haemoglobin and iron status: a randomised controlled trial in malnourished HIV-positive African adults starting antiretroviral therapy. Br J Nutr 2015; 114: 387-97. doi: 10.1017/S0007114515001920.


Chisenga CC, Filteau S, Siame J, Chisenga M, Prendergast AJ, Kelly P. T-cell subsets predict mortality in malnourished Zambian adults initiating antiretroviral therapy. PLoS One 2015; 10: e0129928. doi: 10.1371/journal.pone.0129928.


Bestawros M, Chidumayo T, Blevins M, Canipe A, Bala J, Kelly P, Filteau S, Shepherd BE, Heimburger DC, Koethe JR. Increased systemic inflammation is associated with cardiac and vascular dysfunction over the first 12 weeks of antiretroviral therapy among undernourished, HIV-infected adults in Southern Africa. J AIDS Clin Res 2015; 6: 3. doi:10.4172/2155-6113.1000431.


Kayamba V, Bateman AC, Asombang A, Shibemba A, Zyambo K, Banda T, Soko R, Kelly P. HIV infection and domestic smoke exposure, but not human papillomavirus, are risk factors for oesophageal squamous cell carcinoma in Zambia: a case-control study. Cancer Med 2015; 4: 588-95. doi: 10.1002/cam4.434.


Filteau S, PrayGod G, Kasonka L, Woodd S, Rehman AM, Chisenga M, Siame J, Koethe JR, Changalucha J, Michael D, Kidola J, Manno D, Larke N, Yilma D, Heimburger DC, Friis H, Kelly P. Effects on mortality of a nutritional intervention for malnourished HIV-infected adults referred for antiretroviral therapy: a randomised controlled trial. BMC Medicine 2015; 13:17.

doi: 10.1186/s12916-014-0253-8.


Rehman AM, Woodd S, PrayGod G, Chisenga M, Siame J, Koethe JR, Heimburger DC, Kelly P, Friis H, Filteau S. Effects on anthropometry and appetite of vitamins and minerals given in lipid nutritional supplements for malnourished HIV-infected adults referred for antiretroviral therapy: results from the NUSTART randomised controlled trial. J Acquir Immune Defic Syndr 2015; 68: 405–412.  doi: 10.1097/QAI.0000000000000483.


Rehman AM, Chisenga M, Siame J, Sampson G, Woodd S, Praygod G, Koethe JR, Kelly P, Filteau S. Appetite testing in HIV-infected African adults recovering from malnutrition and given antiretroviral therapy (ART). Public Health Nutr 2015; 18: 742-51. doi: 10.1017/S136898 0014000718.  


Zulu J, Mwansa-Lisulo M, Besa E, Kaonga P, Chisenga CC, Chomba M, Simuyandi M, Banda R, Kelly P. Improving validity of informed consent for biomedical research in Zambia using a laboratory exposure intervention. PLOS One 2014; 9: e108305. doi: 10.1371/journal.pone.0108305.


Canipe A, Chidumayo T, Blevins M, Bestawros M, Bala J, Kelly P, Filteau S, Shepherd BE, Heimburger DC, Koethe JR. A 12 week longitudinal study of microbial translocation and systemic inflammation in undernourished HIV-infected Zambians initiating antiretroviral therapy. BMC Infect Dis 2014; 14: 521. doi: 10.1186/1471-2334-14-521.


Mwanza-Lisulo M, Kapulu MC, Banda R, Sinkala E, Kayamba V, Sianongo S, Kelly P. Adjuvant potential of low dose all-trans retinoic acid during oral typhoid vaccination in Zambian men. Clin Exp Immunol 2014; 175: 468-75. doi: 10.1111/cei.12238.


Asombang A, Kayamba V, Turner-Moss E, Banda L, Colditz G, Mudenda V, Zulu R, Sinkala E, Kelly P. Gastric malignancy survival in Zambia, Southern Africa: A two year follow-up study. Med J Zambia 2014; 41: 13-18.


Kayamba V, Chomba MS, Kelly P. Short term micronutrient-antioxidant supplementation has no impact on a serological marker of gastric atrophy in Zambian adults: retrospective analysis of a randomised controlled trial. BMC Gastroenterology 2014; 14: 52. doi: 10.1186/1471-230X-14-52.


Louis-Auguste J, Greenwald S, Simuyandi M, Soko R, Banda R, Kelly P. High dose multiple micronutrient supplementation improves villous morphology in environmental enteropathy without HIV enteropathy: results from a double-blind randomised placebo controlled trial in Zambian adults. BMC Gastroenterology 2014; 14: 15. doi: 10.1186/1471-230X-14-15.


Jacobs C, Chiluba C, Phiri C, Mwanza-Lisulo M, Hill P, Ijaz S, Kelly P. Seroepidemiology of Hepatitis E virus infection in an urban population in Zambia: strong association with HIV and environmental enteropathy. J Infect Dis 2014; 209: 652-657. doi: 10.1093/infdis/jit409.


Peletz R, Simuyandi M, Simunyama M, Sarenje K, Kelly P, Clasen T. Follow up study to assess the use and performance of household filters in Zambia. Am J Trop Med Hyg 2013; 89: 1190-1194. doi: 10.4269/ajtmh.13-0054.


Payne L, Turner-Moss E, Mutengo M, Asombang A, Kelly P. Prevalence of schistosome antibodies and hepatosplenic signs and symptoms among patients from Kaoma, Western Province, Zambia. BMC Res Notes 2013; 6: 344. doi: 10.1186/1756-0500-6-344.


Kayamba V, Asombang AW, Mudenda V, Lisulo MM, Sinkala E, Mwanamakondo S, Mweemba I, Kelly P. Gastric adenocarcinoma in Zambia: a case-control study of HIV, lifestyle risk factors, and biomarkers of pathogenesis. S Afr Med J 2013; 103: 255-259. doi: 10.7196/samj.6159.


Asombang AW, Kayamba V, Mwanza-Lisulo M, Colditz G, Mudenda V, Yarasheki K, Chott R, Rubin D, Gyawali CP, Sinkala E, Mwanamakondo S, Anderson-Spearie C, Kelly P. Gastric cancer in Zambian adults: a prospective case-control study assessing dietary intake and antioxidant status using isoprostane excretion. Am J Clin Nutr 2013; 97: 1029-1035. doi: 10.3945/ajcn.112.051284.


Peletz R, Simunyama M, Sarenje K, Baisley K, Filteau S, Kelly P, Clasen T. Assessing water filtration and safe storage in households with young children of HIV-positive mothers: a randomized controlled trial in Zambia. PLOSone 2012; 7: e46548. doi: 10.1371/journal. pone.0046548.


Banda R, Yambayamba V, Lalusha BD, Sinkala E, Kapulu MC, Kelly P. Safety of live, attenuated oral vaccines in HIV infected Zambian adults. Oral vaccines in HIV. Vaccine 2012; 30: 5656-5660. doi: 10.1016/j.vaccine.2012.06.079.


Peletz R, Simuyandi M, Sarenje K, Baisley K, Kelly P, Filteau S, Clasen T. Drinking water quality, feeding practices and diarrhea among children under 2 years of HIV-positive mothers in peri-urban Zambia. Am J Trop Med Hyg 2011; 85: 318-326. doi: 10.4269/ajtmh.2011.11-0140.


Psutka R, Peletz R, Michelo S, Kelly P, Clasen T. Assessing the microbiological performance and potential cost of boiling drinking water in urban Zambia. Env Sci Technology 2011; 45: 6095-6101. doi: 10.1021/es2004045.


Harris J, Kelly P, Filteau S. Interactions between HIV, dietary diversity and socio-economic position in an urban African setting. Med J Zambia 2011; 37: 56-61.


Kapulu MC, Simuyandi M, Sianongo S, Mutale M, Katubulushi M, Kelly P.  Differential changes in expression of intestinal antimicrobial peptide genes during Ascaris lumbricoides infection in Zambian adults do not respond to helminth eradication. J Infect Dis 2011; 203: 1464-1473.


Sinkala E, Katubulushi M, Sianongo S, Obwaller A, Kelly P. In a trial of the use of miltefosine to treat HIV-related cryptosporidiosis in Zambian adults, extreme metabolic disturbances contribute to high mortality. Ann Trop Med Parasitol 2011; 105: 129-134.


Hardwick RJ, Machado LR, Zuccherato LW, Antolinos S, Xue Y, Shawa N, Gilman RH, Cabrera L, Berg DE, Tyler-Smith C, Kelly P, Tarazona-Santos E, Hollox EJ. A worldwide analysis of beta-defensin copy number variation suggests recent selection of a high-expressing DEFB103 gene copy in East Asia. Hum Mutation 2011; 32: 743-750.


Dhaliwal W, Shawa T, Khanam M, Jagatiya P, Simuyandi M, Ndulo N, Bevins CL, Sanderson IR, Kelly P. Intestinal antimicrobial gene expression: impact of micronutrients in malnourished adults during a randomised trial. J Infect Dis 2010; 202: 971-978.


Kelly P, Shawa T, Mwanamakondo S, Soko R, Smith G, Barclay GR, Sanderson IR. Gastric and intestinal barrier impairment in tropical enteropathy and HIV: limited impact of micronutrient supplementation during a randomised controlled trial. BMC Gastroenterology 2010; 10: 72.


Papadia C, Kelly P, Caini S, Corazza GR, Shawa T, Franze A, Forbes A, Di Sabatino A. Plasma citrulline as a quantitative biomarker of HIV-associated villous atrophy in a tropical enteropathy population. Clin Nutr 2010; xx: 1-6.


Kingori P, Muchimba M, Sikateyo B, Amadi B, Kelly P. ‘Rumours’ and clinical trials: a retrospective examination of a paediatric malnutrition study in Zambia. BMC Public Health 2010; 10: 556.


Amadi B, Mwiya M, Sianongo S, Payne L, Watuka A, Katubulushi M, Kelly P. High dose prolonged treatment with nitazoxanide is not effective for cryptosporidiosis in HIV positive Zambian children: a randomised controlled trial. BMC Infect Dis 2009; 9: 195.


Sinkala E, Gray S, Zulu I, Mudenda V, Zimba L, Vermund S, Drobniewski F, Kelly P. Clinical and ultrasonographic features of abdominal tuberculosis in HIV positive adults in Zambia. BMC Infect Dis 2009; 9: 44.


Dhaliwal W, Kelly P, Bajaj-Elliott M. Differential effects of Staphylococcal enterotoxin B (SEB)-mediated immune activation on constitutive and inducible small intestinal defensins. Clin Exp Immunol 2009; 156: 263-70.


Shawa TS, Sianongo S, Akokwa I, Mwansa J, Nchito MF, Kelly P. Changes in serum cytokine concentration after praziquantel treatment in Zambian children with schistosomiasis. Med J Zambia 2009; 36: 6-12.


Amadi B, Fagbemi A, Kelly P, Mwiya M, Torrente F, Salvestrini C, Day RM, Golden MH, Eklund E, Freeze HH, Murch SH. Reduced production of sulfated glycosaminoglycans occurs in Zambian children with kwashiorkor but not marasmus. Am J Clin Nutr 2009; 89: 592-600.


Kelly P, Todd J, Sianongo S, Mwansa JCL, Sinsungwe H, Katubulushi M, Farthing MJG, Feldman RAF. Susceptibility to intestinal infection and diarrhoea in Zambian adults in relation to HIV status and CD4 count. BMC Gastroenterology 2009; 9: 7.


Zulu I, Njobvu L, Hassan G, Shawa T, Kelly P. Cytokine activation is predictive of mortality in Zambian patients with AIDS-related diarrhoea. BMC Infect Dis 2008; 8: 156.


Kelly P, Katubulushi M, Todd J, Banda R, Yambayamba V, Fwoloshi M, Zulu I, Kafwembe E, Yavwa F, Sanderson IR, Tomkins A. Micronutrient supplementation has a limited effect on intestinal infectious disease and mortality in a Zambian population of mixed HIV status: a cluster randomized trial. Am J Clin Nutr 2008; 88: 1010-1017.


Kaile T, Zulu I, Lumayi R, Ashman N, Kelly P. Inappropriately low aldosterone concentrations in adults with AIDS-related diarrhoea in Zambia; a study of response to fluid challenge. BMC Research Notes 2008; 1:10.


Kelly P, Katema M, Amadi B, Zimba L, Aparicio S, Mudenda V, Baboo KS, Zulu I. Gastrointestinal pathology in the University Teaching Hospital, Lusaka, Zambia - review of endoscopic and pathology records.  Trans Roy Soc Trop Med Hyg 2008; 102: 194-199.


Kelly P, Bajaj-Elliott M, Katubulushi M, Zulu I, Poulsom R, Feldman RA, Bevins CL, Dhaliwal W. Reduced gene expression of intestinal a-defensins predicts diarrhoea in a cohort of Zambian adults. J Infect Dis 2006; 193: 1464-1470.


Mwiya M, Amadi B, Kelly P. Intestinal infection before and after nutritional rehabilitation in children recovering from persistent diarrhoea. Med J Zambia 2006; 7: 19-21.


Zulu I, Kelly P, Njobvu L, Sianongo S, Kaonga K, McDonald V, Farthing M, Pollok R. Nitazoxanide for persistent diarrhoea in Zambian AIDS patients: a randomized controlled trial. Aliment Pharmacol Therap 2005; 21: 757-763.


Amadi B, Mwiya M, Kelly P, Thomson M, Walker-Smith JA. Improved nutritional recovery on an elemental diet in Zambian children with persistent diarrhoea and malnutrition. J Trop Paediatr 2005; 51: 5-10.


Baboo KS, Zulu I, Sianongo S, Kaonga K, Mwenya D, Mwansa JCL, Pollok RCG, Kelly P. Intestinal infection in adults in an urban Zambian population in relation to immune status. Med J Zambia 2004; 6: 104-110.


Kelly P, Menzies I, Crane R, Zulu I, Nickols C, Feakins R, Mwansa J, Mudenda V, Katubulushi M, Greenwald S, Farthing MJG. Responses of small intestinal architecture and function over time to environmental factors in a tropical population. Am J Trop Med Hyg 2004; 70: 412-419.


Kelly P, Feakins R, Domizio P, Murphy J, Bevins CL, Wilson J, McPhail G, Bajaj-Elliot M, Poulsom R, Dhaliwal W. Paneth cell granule depletion in the human small intestine under infective and nutritional stress. Clin Exp Immunol 2004; 135: 303-309.


Dhaliwal W, Bajaj-Elliott M, Kelly P. Intestinal defensin gene expression in human populations. Molec Immunol 2003; 40: 469-475.


Kelly P, Hicks S, Oloya J, Mwansa JCL, Sikakwa L, Zulu I, Phillips AD. Escherichia coli enterovirulent phenotypes in Zambians with AIDS-related diarrhoea. Trans Roy Soc Trop Med Hyg 2003; 97: 573-576.


Guinness L, Walker D, Ndubani P, Jama J, Kelly P. Surviving the impact of HIV-related illness in the Zambian business sector. AIDS Patient Care and STDs 2003; 7: 353-363.


Amadi BC, Mwiya M, Musuku J, Watuka A, Sianongo S, Ayoub A, Kelly P. Effect of nitazoxanide on morbidity and mortality in Zambian children with cryptosporidiosis: a randomised controlled trial. Lancet 2002; 360: 1375-1380.


Kelly P, Zulu I, Amadi B, Munkanta M, Banda J, Rodrigues LC, Mabey D, Feldman R, Farthing, MJG. Morbidity and nutritional impairment in relation to CD4 count in a Zambian population with high HIV prevalence. Acta Tropica 2002; 83: 151-158.


Zulu I, Veitch A, Sianongo S, McPhail G, Feakins R, Farthing MJG, Kelly P. Albendazole chemotherapy for AIDS-related diarrhoea in Zambia – clinical, parasitological and mucosal responses. Aliment Pharm Therap 2002; 16: 595-601.


Mwansa JCL, Mutela K, Zulu I, Amadi BC, Kelly P. Antimicrobial resistance in enterobacteria from African AIDS patients. Emerging Infect Dis 2002; 8: 92-93. Erratum: 8: 540;


Veitch A, Kelly P, Zulu I, Segal I, Farthing MJG. Tropical enteropathy: a T cell mediated crypt hyperplastic enteropathy. Eur J Gastroenterol Hepatol 2001; 13: 1175-1181.


Kelly P, Musuku J, Kafwembe E, Libby G, Zulu I, Murphy J, Farthing MJG. Impaired bioavailability of vitamin A in adults and children with persistent diarrhoea in Zambia. Aliment Pharmacol Therap 2001; 15: 973-979.


Fernando N, Holton J, Zulu I, Vaira D, Mwaba P, Kelly P. Helicobacter pylori infection in an urban Zambian population.  J Clin Micro 2001; 39: 1323-1327.


Amadi BC, Kelly P, Mwiya M, Mulwazi E, Sianongo S, Changwe F, Thomson M, Hachungula J, Watuka A, Walker-Smith JA, Chintu C. Intestinal and systemic infection, HIV and mortality in Zambian children with persistent diarrhoea and malnutrition.  J Ped Gastroenterol Nutr 2001; 32: 550-554.


Sianongo S, McDonald V, Kelly P. A technique for detection of microsporidia adapted for use in developing countries. Trans Roy Soc Trop Med Hyg 2001; 95: 605-607.


Kafwembe E, Kelly P, Ngalande P. Vitamin A in HIV infection and AIDS. E Afr Med J 2001; 78: 451-453.


Veitch AM, Kelly P, Zulu I, McDonald TT, Farthing MJG. Lack of evidence for small intestinal mucosal T cell activation as a pathogenic mechanism in African HIV-associated enteropathy. Dig Dis Sci 2001; 46: 1133-1138.


Kelly P, Jack D, Naeem A, Pollok R, Mandanda B, Klein N, Turner M, Farthing MJG. Mannose Binding Lectin is a contributor to mucosal defence against Cryptosporidium parvum in AIDS patients. Gastroenterology 2000; 119: 1236-1242.


Zulu I, Kelly P, Veitch A, Mwansa J, Farthing MJG. Contrasting incidence of Clostridium difficile in AIDS patients in London and Lusaka. Trans Roy Soc Trop Med Hyg 2000; 94: 167-168.


Kelly P, Musonda R, Kafwembe E, Kaetano L, Keane E, Farthing MJG. Micronutrient supplementation for the AIDS diarrhoea-wasting syndrome in Zambia: a randomised controlled trial. AIDS 1999; 13: 495-500.


Kelly P, Makumbi FA, Carnaby S, Simjee AE, Luo NP, Farthing MJG. Variable distribution of Cryptosporidium parvum in small and large intestine in AIDS revealed by polymerase chain reaction. Eur J Gastro Hepatol 1998; 10: 855-858.


Kelly P, Feldman RA, Ndubani P, Baboo KS, Timæus I, Farthing MJG, Wallman S. High adult mortality in Lusaka. Lancet 1998; 351: 883. [Research Letter].


Ballinger A, Kelly P, Hallyburton E, Besser R, Farthing MJG. Plasma leptin in chronic inflammatory bowel disease and HIV: implications for the pathogenesis of anorexia and weight loss. Clin Sci 1998; 94: 479-483.


Nchito M, Kelly P, Sianongo S, Luo NP, Feldman RA, Farthing MJG, Baboo KS. Cryptosporidiosis in urban Zambian children: an analysis of risk factors. Am J Trop Hyg 1998; 59: 435-437.


Ndubani P, Kelly P, Farthing MJG, Wallman S. Local understandings of adult diarrhoeal disease and its treatment in an area of high HIV seroprevalence in Zambia.  Trop Med Int Health 1998; 3: 783-787.


Veitch AM, Kelly P, Segal I, Spies SK, Farthing MJG. Does sucrase deficiency in black South Africans protect against colonic disease? Lancet 1998; 351: 183. [Research Letter].


Kelly P, Nchito M, Baboo KS, Ndubani P, Okeowo NP, Luo NP, Feldman RA, Farthing MJG. Cryptosporidiosis in adults in Lusaka, Zambia, and its relationship to oocyst contamination of drinking water. J Infect Dis 1997; 176: 1120-1123.


Kelly P, Davies SE, Mandanda B, Veitch A, McPhail G, Zulu I, Drobniewski F, Fuchs D, Summerbell C, Luo NP, Pobee JOM, Farthing MJG. Enteropathy in Zambians with HIV related diarrhoea: regression modelling of potential determinants of mucosal damage. Gut 1997; 41: 811-6.


Kelly P, Summerbell C, Ngwenya B, Mandanda B, Hosp M, Luo N, Fuchs D, Wachter H, Pobee JOM, Farthing MJG. Systemic immune activation as a potential determinant of wasting in Zambians with HIV related diarrhoea. Q J Med 1996; 89: 831-837.


Kelly P, Lungu F, Keane E, Baggaley R, Kazembe F, Pobee JOM, Farthing MJG. Albendazole chemotherapy for treatment of diarrhoea in patients with AIDS in Zambia: a randomised double blind controlled trial. BMJ 1996: 312: 1187-1191.


Kelly P, Baboo KS, Woolf M, Ngwenya B, Luo N, Farthing MJG. Prevalence and aetiology of persistent diarrhoea in adults in urban Zambia. Acta Tropica 1996; 61: 183-190.


Thompson A, Hughes M, Anastasova S, Conklin L, Thomas T, Leggett C, Faubion W, Miller T, Delaney P, Lacombe L, Loiseau S, Meining A, Richards-Kortum R, Tearney G, Kelly P, Yang G-Z. The potential role of optical biopsy in the study and diagnosis of environmental enteric dysfunction. Nat Rev Gastroenterol Hepatol; in press.


Louis-Auguste J, Kelly P. Tropical enteropathies. Current Gastroenterology Reports 2017; in press.


Kayamba V, Heimburger DC, Morgan DR, Atadzhanov M, Kelly P. Exposure to biomass smoke as a risk factor for oesophageal and gastric cancer in low-income populations: a systematic review. Malawi Med J 2017; in press.


Owino V, Ahmed T, Freemark M, Kelly P, Loy A, Manary M, Loechl C. Environmental Enteric Dysfunction and Growth Failure/Stunting in Global Child Health. Pediatrics 2016, e20160641. doi: 10.1542/peds.2016-0641.


Trehan I, Kelly P, Shaikh N, Manary MJ. New insights into Environmental Enteric Dysfunction. Arch Dis Child 2016; 101: 741-4. doi: 10.1136/archdischild-2015-309534.


Prendergast A, Kelly P. Interactions between intestinal pathogens, enteropathy and malnutrition in developing countries. Curr Op Infect Dis 2015; 29; 229-236. doi: 10.1097/QCO.0000000000000261.


Mwanza-Lisulo M, Kelly P. Potential for use of retinoic acid as an oral vaccine adjuvant. Phil Trans Roy Soc B 2015; 370: 20140145. doi: 10.1098/rstb.2014.0145.


Chisenga CC, Kelly P. A review of human Selenium requirements, disease and immune function. Med J Zambia 2015; in press.


Kelly P, Saloojee H, Chen J, Chung RT. Non-communicable disease in HIV infected adults in Africa: gastrointestinal, hepatic and nutritional disorders. JAIDS 2014; 67 Suppl 1: S79-86. doi: 10.1097/QAI.0000000000000260..


Prendergast A, Kelly P. Enteropathies in the developing world; neglected effects on global health. Am J Trop Med Hyg 2012; 86: 756-763.


Asombang AW, Kelly P. Gastric cancer in Africa: what do we know about incidence and risk factors? Trans Roy Soc Trop Med Hyg 2012; 106: 69-74.


Kelly P. Treatment and prevention of cryptosporidiosis: what options are there for a country like Zambia? Parasitology 2011; 138: 1488-1491.


Kelly P. Nutrition, intestinal defence, and the microbiome. Proc Nutr Soc 2010; 69: 261-268.


Kelly P. Vitamin A metabolism to retinoic acid and its possible implications in HIV/AIDS. Med J Zambia 2009; 36: 51-57.


Hughes S, Kelly P. Interaction between malnutrition and immunity to parasites. Parasite Immunol 2006; 28: 577-588.

Shawa ST, Nchito M, Mwansa JCL, Kelly P. Schistosomiasis – a public health problem. Med J Zambia 2006; 7: 5-7.


Pollok R, Zulu I, Kelly P. HIV and the gut. Int J Gastroenterol 1999; 4: 13-15.

bottom of page